a What is the stimulus for erythropoietin production b Where

a. What is the stimulus for erythropoietin production?

b. Where are the production cells for erythropoietin?

c. Where are the target cells for erythropoietin?

d. What is the cell action and response caused by erythropoietin?

Solution

a. The specific stimulus for erythropoietin production is due to Epo expression that causes when there is a fall in tissue O₂ pressure specially increases under hypoxic conditions in the kidneys

b. Primarly the kidney cells that make erythropoietin. Erythropoietin is produced by interstitial fibroblasts in the kidney and also produced in perisinusoidal cells in the liver. liver production predominates in the fetal.

c. Erythropoietin (EPO) is a hormone targets the bone marrow for the prodcution of red blood cells

d. Erythropoietin is the harmone also a type of cyto kine singnalling molecule which stimulate bone marrow for RBC prodcution. It is primary erythropoietic factor that cooperates with various other growth factors (e.g., IL-3, IL-6, glucocorticoids, and SCF) and make involved in the development of erythroid lineage from multipotent progenitors in bne marrow.