The termination of translation requires which of the followi

The termination of translation requires which of the following? Select all that apply. terminator tRNA E site of the ribosomal complex stop codon on the mRNA release factors

Solution

Answer

1. To terminate translation Stop codon and release factors are required. The completion of the peptide chain is signaled by the stop codons and as the cells lacks tRNAs with anticodons complementary to the termination signals, the release factors recognize the signals and terminates the translation process. The termination process requires GTP hydrolysis.

Thus, the correct answers are option (3), (4), and (5).

2. True statements:

The genetic code is non-overlapping as each 3 bases is read one after the other.

Translation process starts at the start codon AUG which is recognized by the Met-tRNA to ensure the correct reading frame. Therefore, the start codon or initiation codon sets the reading frame.

Therefore, the correct answers are option (4) and option (5).

3. Transfer-messenger RNA (tmRNA) is a bacterial RNA with dual tRNA-like and mRNA-like properties. In trans-translation process, the tmRNA and its associated proteins bind to the stalled bacterial ribosomes on the broken mRNA in the middle of protein synthesis and facilitate the degradation of the broken mRNA. Therefore, the correct answer is option (a).

4. The folding of polypeptides into alpha helices and beta-pleated sheet depends on the pattern of hydrogen bonding present between the peptide N-H and C = O groups of the amino acids that are present in a liner fashion. Thus, the correct answer is option (e).