Liposomes were constructed for an experiment with liver cell

Liposomes were constructed for an experiment with liver cells in culture. The experiment will be at 25°C and not 37°C. Which change would NOT increase liposome fluidity at the lower temperature?

factors of fuildity are

--> ratios of different types of lipids

--> saturated vs. unsaturated phospholipids

--> amount of cholesterol

1. increasing the concentration of sterols

2.increasing the concentration of mono-unsaturated fatty acids in phospholipids (true)

3.increasing the concentration of polyunsaturated fatty acids in phospholipids

4.decreasing the concentration of saturated fatty acids in sphingolipids

5.increasing the concentration of triacylglycerol in liposomes

Solution

Membrane fluidity refers to the viscosity of lipid bilayer of a cell membrane. Lipid packing can influence the lipidity of the membrane.

Factors determining the membrane fluidity:

The correct answer is Option 2.