If genes abc and d are genetically linked to each other does

If genes a,b,c, and d are genetically linked to each other, does it follow that a recombination experiment would detect genetic linkage between a and d? Assume a b c d is the order of the genes on the chromosome. Explain your answer.

Solution

If genes a,b,c, and d are genetically linked to each other, then it does follow that a recombination experiment would detect genetic linkage between a and d because a & d genes are apart from each other on the same chromosome therefore, it is possible to occur crossing over. Therefore, it is enough for these two genes to undergo independent assortment. Crossing over is somewhat randomly distributed over the length of the chromosome because if the two genes are close together then it is very easy to get exchange of chromosomal breaks therefore, if the two genes are located farther apart then there will be higher room for the exchange of genetic material with chromosomal breaks. Therefore, when two genetic are far apart on the same chromosome are more likely to have a crossover between them than two loci that are close together.

Therefore, linked genes due to linkage often do not obey Mendel\'s laws of inheritance such as independent assortment because of crossing over with reciprocal exchange of hereditary genetic material meticulously in between non-sister chromatids of homologous chromosomes at the time of synapsis formation in reduction division or meiosis