2 Which oligonucleotide segment that could base pair with a

2. Which oligonucleotide segment that could base pair with a DNA strand with the sequence 5\'-ATG-3\' to form a double-stranded DNA helix. Briefly explain your answer, including an explanation of why each other answer choice is incorrect. (C) (A) (B) (D) Thymine Thymine Cytosine Cytosine OH OH Adenine Adenine Adenine Adenine OH OH O Cytosine O Thymine O Cytosine Thymine OH OH

Solution

option B.

given sequence, 5\'-ATG-3\'

complementary sequence, 3\'-TAC-5\'

among the above four options, \'C\' and \'D\' are ribose sugars (contain 2\' OH). But the sequence in the question is DNA (deoxyribonucleic acid). therefore, we can eliminate \'C\' and \'D\'.

among \'A\' and \'B\', A- 5\'-TAC-3\'

B- 3\'-TAC-5\'. In opton B, 5\' carbon of \'T\' is connected to 3\' carbon of \'A\', similarly, 5\' carbon of \'A\' is connected to 3\' carbonn of \'C\'. this sequence-- 3\'-TAC-5\'