Presynaptic stimulation causes release of neurotransmitter t

Presynaptic stimulation causes release of neurotransmitter that acts at isotropic the What ion(s) pass(es) through postsynaptic receptors to elicit the observed responses. receptor\'s ion channel, and which direction does the ion(s) go.

Solution

Ca²⁺ or calcium ions play a significant role in the neural facilitation. This theory is also known as the residual Ca²⁺ theory proposed by Katz and Miledi . They said that the neurotransmitter release was due to the residual or accumulated active calcium within the axon membrane. These help in transmitting the signals across the chemical synapses.

Voltage gated channels for Ca²⁺ are located within the presynaptic terminal. The Ca²⁺ enters into these terminals when an action potential invades the presynaptic membrane. The synaptic vesicles fuse to the synaptic membrane because of a higher concentration of the Ca²⁺ and release the neurotransmitters into the synaptic cleft. These neurotransmitters contact the receptors present in the postsynaptic membrane. the release of the neurotransmitter corresponds to the influx of the Ca²⁺ . Short term facilitations are alsoformed as a result of build up of active calcium within the presynaptic terminal.