A hormone binds a receptor and activates the cAMP signal tra
A hormone binds a receptor and activates the cAMP signal transduction pathway ultimately leading to the cell response. Which of the following is NOT a likely mechanism for downregulating cAMP transduction?
(I`m leaning towards D but I`m looking for more insight.)
| a. | The hormone dissociating from the receptor. |
Solution
Activate adenylyl cyclase is a key step in which the enzyme turns adenosine triphosphate into cyclic adenosine monophosphate. This is a required step to move forward as cAMP dependent pathway because cAMP is a secondary messenger. The activation step of adenylyl cyclase is achieved by Gs alpha subunit of G protein complex. So option d is correct.
