Which of the following would increase the rate of glucose up

Which of the following would increase the rate of glucose uptake in cultured liver cells? Transfect cells with the wild-type GLUT-1 gene. Increase the concentration of glucose in the medium. Decrease the concentration of calcium in the medium. Decrease the concentration of glucose in the medium. Both A and B Active transport does NOT include: diffusion. osmosis. Both A and B These are all passive.

Solution

E. This is so because GLUT-1 is a known glucose transporter. This makes the glucose transport across plasma membrane possible. This will thus increase the rate of glucose. Also, if glucose concentration is higher in the medium, it will move down the concentration gradient which will result in faster rate of glucose transport across the cell. D. Both diffusion and osmosis occur down the concentration gradient and don’t need active transport.