Do activators in bacteria work on yeastSolutionThe bacteria

Do activators in bacteria work on yeast?

Solution

The bacteria is the prokaryote organism which is most primitive organism. In bacteria, the transcription factor binding sites almost occur close to transcription start site while in eukaryotes, the transcription factor binding sites tend to occur further away from the transcription site. In some cases, the transcription factor binding site can be very far away.

The Activators in bacteria does not work on yeasts because in yeast the transcriptional machinery is not bound to the promoter prior to activation. Yeast activators have separable activating and DNA binding domains. In yeasts, an activating region must be tethered to DNA near a promoter to activate transcription.