1 Which of these binds a ligand and undergoes a conformation

1.) Which of these binds a ligand and undergoes a conformational change to allow ion flux across the membrane?

a.) Channel

b.) Transporter

c.) Enzyme

d.) G-protein coupled receptor

2.) Which of these operates with molecules that can diffuse through the cell membrane (e.g. steroid hormones)?

a.) Ligand gated channels

b.) Enzyme/enzyme linked receptors

c.) G protein-coupled receptors

d.) intracellular receptors

Solution

1.

Ligand gated ion channel proteins are activated in response to the binding of a ligand. The ligand binds at an allosteric binding site that is independent of the channel protein’s pore. This biding causes a conformational change in the structure of the channel protein, which in turn causes ion influx.

Hence, the correct option is (a) Channel.