For each of the following instances of DNA damage determine
For each of the following instances of DNA damage, determine the nature of the mutation that will occur if the damage is not repaired, and which DNA repair mechanism is likely to fix the problem. An example is shown.
Solution
Answer:
11) 2) DEAMINATION OF CYTOSINE- C-U (CYTOSINE TO URACIL) RELEASING AMMONIA- BASE EXCISION REPAIR.
3) PYRIMIDINE DIMER- FORMED FROM THYMINE (OR) CYTOSINE BASES IN DNA- NUCLEOTIDE EXCISION REPAIR.
4) METHYLATION OF THE OXYGEN OF CARBON 6 OF GUNANINE (O-6) METHYL GUNANINE- C-T (TRANSITION) MUTATION- BASE EXCISION REPAIR.......................
