Which of the following are mostly likely to be antibioticsen
Which of the following are mostly likely to be antibiotic-sensitive? (Choose the one correct answer)
Archaea
Gram-negative bacteria
Eukaryotes
Protists
Bacteria with lots of peptidoglycan
Bacteria with little or no peptidoglycan
| A. | Archaea | |
| B. | Gram-negative bacteria | |
| C. | Eukaryotes | |
| D. | Protists | |
| E. | Bacteria with lots of peptidoglycan | |
| F. | Bacteria with little or no peptidoglycan | 
Solution
antibiotics are formulated to kill bacteria. therefore, options B, E and F can be considered.
different classes of antinotics have distinct modes of mechanism.
some antibiotics target bacterial cellwall (for example, penicillin, cephalosporin)
some antibiotics target cell membrane (polymyxins)
some target bacterial enzymes (rifampicin, sulphonamides)
some target protein synthesis (macrolides, tetracyclines)
broad spectrum antibiotics target wide range of bacteria. while narrow spectrum antibiotics target specific class of bacteria.
if a specific class of antibiotic is given, then it would be easy to answer.
but most of the antibiotics target bacterial cell wall, therefore, option would be most probably E.

