Imagine that you set up a threepoint mapping cross to determ

Imagine that you set up a three-point mapping cross to determine the order of three X-linked genes. You have recessive mutations available for all three genes: yellow (y). white (iv) and echinus. A heterozygous F| Drosophila female is crossed to a mutant male. The observed numbers and phenotypes of F_2 are as follows: 46S5 yellow, white, echinus 4759 wild type SO yellow 70 white, echinus 193 yellow, white 207 3 yellow, echinus 3 white Based on this data answer the questions in the following order (each answer yields a clue useful in following question): Determine which of the above phenotypic classes represent the parental types and the recombinant types (specify SCO. DCO). Identify the reciprocal classes of phenotypes. Determine which gene is in the middle. Calculate the recombination frequency (% RF) based on the observed F_2 numbers of each pair of reciprocal classes. Calculate the gene distances. (0 draw a genetic map of the 3 genes (include the gene location, symbol and m. u. between neighboring genes).

Solution

Primary, Secondary, and tertiary structures would be altered

Frameshift mutation could change the amino acid sequence therby altering Primary, Secondary, and tertiary structures would be altered.