Whene does the testosterone converted to dihydrotestosterone

Solution

Testosterone is the primary hormone (androgen) secreted by the testes. It is converted to dihydrotestosterone (DHT) by the action of enzyme 5 alpha reductase. This enzyme also regulates how much and how rapidly free testosterone needs to be converted to DHT. This enzyme is present most of the tissues including brain, skin, and genitals except for skeletal muscles. DHT is 3-5 times more potent androgen than testosterone as it has more affinity towards the androgen receptor. During puberty, the burst of DHT determines how the genitals (sex organs) are developed as well as sexual orientation and attraction towards other people of same or different gender. The rate of conversion of testosterone to DHT is genetically determined. Every individual’s testosterone to DHT conversion is regulated via genes.