There are two binding sites for acetylcholine on its recepto

There are two binding sites for acetylcholine on its receptor. What would be the shape of the Hill plot if there was cooperativity of binding?

Select one:

a. Hyperbolic

b. Linear

c. Sigmoidal, with a sharp change in slope

d. Two sigmoidal areas linked together, one for each binding event

e. Two sigmoidal lines, one higher than the other on the graph

I\'m pretty positive that it\'s d, but not 100%.

Thank you so much!

Solution

Yes your and D is correct

Two sigmoidal areas linked together, one for each binding event

acetylcholine receptors bound acetylcholine in a cooperative manner due to the existence of several binding sites. the plot will be non linear