Calculate creatinine clearance given the following informati

Calculate creatinine clearance, given the following information: serum creatinine, 1.2 mg/dL; urine creatinine, 120 mg/dL; urine volume, 1750 m1724h; body surface area, 1.80 m^2.

Solution

According to Dubois and Dubois creatinine clearance can be calculated as:

Creatinine clearance = (Urine creatinine X Urine volume) (1.73)/ (Plasma creatinine X Time X Body Surface Area)

=> Creatinine clearance = (120 X 1750 X 1.73)/ (1.2 X 1440 X 1.8) = 363,300/3110.4

Creatinine clearance = 116.80 mL/min/1.73m²