What is the expected allele frequency for a codominant genet
What is the expected allele frequency for a codominant genetic disease with a selection coefficient of 0.45 and a forward mutation rate of 5.2 x 10-5 (assume the heterozygotes have a perfectly intermediate fitness)? Show your work
Solution
Selection coefficient (S)=0.45
Forward mutation rate (u) = 5.2 x 10-5
What is the expected allele frequency for a co dominant genetic disease= q = (u/s)1/2=(5.2 x 10-5/0.45) 1/2=0.01075 or 1.075%
