Which of the following is FALSE regarding the ion channels f

Which of the following is FALSE regarding the ion channels found in nerves? a) the soma may contain ligand-gated channels, which can open or close in response to the binding of a protein to the channel, thus creating a graded potential b) there are voltage gated calcium channels in the axon terminal, which open and allow calcium to flow into the axon terminal releasing neurotransmitters into the synapse c) there are potassium leak channels in the membrane, which can open and close in response to the binding of a ligand and thus help maintain the resting membran potential of -70mv. d) both A and B e) both A and C

Solution

Answer: (e) Both A and C.

Ligand-gated channels, located at sites of synaptic contact are found predominantly on dendritic spines, dendrites and somata of nerve cells, or neurons. Ligand gated ion channels are responsible for creating graded potential upon binding of a ligand, inclusing amino acids but not proteins.

There are voltage gated calcium channels in the axon terminal, which open and allow calcium to flow into the axon terminal releasing neurotransmitters into the synapse.

The potassium leak channels in the membrane can open and close under resting cellular conditions and thus help maintain the resting membran potential of -70mv. Upon binding of a ligand, the neuron initiates an action potential combined with opening and closing of voltage-gated ion channels.