The biosynthetic pathway for the two amino acids E and H is

The biosynthetic pathway for the two amino acids E and H is shown schematically to the right. After showing that E inhibits Enzyme 6, and H inhibits Enzyme 3 you predict that Enzyme 1 will be most efficiently controlled via feedback inhibition by molecule:

C

E

H

E and H

23. The biosynthetic pathway for the two amino acids E and His shown schematically to the right. After showing that E inhibits Enzyme 6, and H inhibits Enzyme 3 you predict that Enzyme 1 will be most efficiently controlled A B C via feedback inhibition by molecule: a. C b. E c. H d. E and H D- E F- G H

Solution

Regulation by feedback: The rate of amino acid biosynthesis depend upon the amount of enzyme present and the activity of those enzymes.

Feedback inhibition: The first reaction that is irreversible in the biosynthesis of amino acids is referred to as a committed step, and the feedback loop of amino acid biosynthesis is a negative one, with the product inhibiting the catalyst in the committed step. This indicates that the biosynthesis of amino acid is regulated by negative feedback mechanism.

The correct answer to this question is option A. The amino acid C will inhibit the enzyme 1.