What is the most abundant iodinated amine in circulation in

What is the most abundant iodinated amine in circulation in humans? MIT rT3 (reverse T3) T3 T4 Which of the following steroids are produced de novo (i.e. from scratch using cholesterol) in the granulosa cell of the ovary? Prenenolone and progesterone Progesterone, androstenedione and testosterone Androstenedione, testosterone and estradiol Progesterone, estradiol and estrone Pregnenolone, progesterone, androstenedione and testosterone

Solution

1.Answer is C.

Most abundant iodinated amine in circulation in humans is T4.

T4 is a thyroxine which is a tyrosine based hormone produced by thyroid gland. It is the major thyronine secreted from thyroid gland.

It is primarily responsible for the regulation of metabolism. It is the most abundant thyroid hormone in circulation and it is viewed as prohormone.

Most of the thyroid hormones that are present in the blood are bound to the transport proteins.

T4 give rise to T3 and r T3 and this conversion occurs by the deionises.These are produced by the follicular cells of thyroid gland. These are regulated by the thyroid stimulating hormones.

2.Answer is A.

Steroids are produced de novo that is from scratch using cholesterol in granulose cell of the ovary is pregnenolone and progesterone.

Pregnenolone is synthesized from cholesterol and and it is produced from gonads, adrenal glands and brain.

In granulose cell of ovary, the pregnenolone get converted into progesterone. It is intermediate or the precursor one in the biosynthesis of the steroid hormones.

Pregnenolone and progesterone are used to rise the hormone levels in the human body. These hormones work together for the concert of life.