a The typical diameter of an alveolus is 03 mm The surface t

a. The typical diameter of an alveolus is 0.3 mm. The surface tension of water is about 70 dyne/cm. The dyne is the unit of force in the cgs system: 1 g*cm/s2. What is the pressure within this alveolus assuming no surfactant at mechanical equilibrium? Give the answer in mm Hg. (Hint: use Law of Laplace for a sphere)

b. Surfactant lowers the surface tension to about 28 dyne/cm. What would the pressure be in an alveolus with a diameter of 0.3 mm?

Solution

Law of laplace for sphere P= (2*Y)/r

Where,

Y=tension=70 dyne

r=radius=0.15mm=0.015cm

Substituting

P= 2*70/0.015 = 9333 dyne/cm-2 = 933.3 Pascal

Using the conversion of 1 mm Hg = 133.4 N m-2

933.3 Pa x 1 mm Hg/133.4 Pa = 7mm Hg

b. Since pressure at a given r is directly proportional to we can calculate the pressure here as a ratio of the pressure in A.It is given as

P1/P2= Y1/Y2

7mm Hg/P2 = 70/28

P2 = 2.8 mm Hg

hope it clears your doubt

a. The typical diameter of an alveolus is 0.3 mm. The surface tension of water is about 70 dyne/cm. The dyne is the unit of force in the cgs system: 1 g*cm/s2.

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