The body normally produces about 2 g of creatinine per day T

The body normally produces about 2 g of creatinine per day. The amount varies with individuals and is approximately proportional to the muscle mass. It is excreted through the kidneys according to Urinary excretion of creatinine = GFR x Plasma concentration of creatinine. A. If the GFR is 120 mL min^-1, what is the plasma concentration of creatinine at steady-state?

Solution

Answer:

Urine creatinine = GFR x Plasma creatinine

The normal urine creatinine value in

                                              Males = 97 to 137 mL/min

                                             Females = 88-128 mL/min

so, we take 130 as the normal urine creatinine value.

    According to given formula,

Urine creatinine = GFR x Plasma creatinine

            130 ml/min = 120 ml/min   x Plasma creatinine

        Plasma creatinine =   130/120

                                      = 1.08 ml/min

                                            or

                                      =15.552   declitre/day or 1.55 litre /day