We have a patient with undigested fats in the feces but panc
We have a patient with undigested fats in the feces but pancreatic function was normal. How could something like this happen?
Solution
Motility disorders that result in rapid gastric emptying and decreased small intestinal transit time may also be associated with malabsorption due to inadequate lipid digestion.Rapid transit causes poor mixing of food together with bile and pancreatic enzymes,further reduces contact time with the small intestine leading to impaired digestion and absorption,and affects the stimulation of pancreatic function.For instance,gastrectomy alters gastric emptying,which reduces lipase production because chyme rapidly bypasses the duodenum resulting in reduced stimulation of duodenal hormones that normally stimulate the pancreas to release enzymes.
It may also be due to liver and gall bladder malfunctioning such as bile acid synthesis defects,biliary tract obstruction by stones.Lipid malabsorption can also be caused by bacterial overgrowth in small intestine in the following way:
