In the human population a deleterious recessive allele respo

In the human population, a deleterious recessive allele responsible for a lethal genetic disease occurs at a frequency of 0.05. What should be the per-generation rate of mutation from the normal allele to the deleterious allele if the persistence of the deleterious allele is to be explained by mutation-selection balance?

Solution

deleterious recessive allele genetic frequency=0.05

per generaton frequency here=1-0.05=0.85

The pergeneration rate=0.85/0.05=17.0