Consider a casecontrol study of red meat consumption and pro

Consider a case-control study of red meat consumption and prostate cancer. There are 350 cases of prostate cancer and 350 controls. 200 cases and 131 controls are known to have been regular consumers of red meat.

a) Create the appropriate 2x2 table and calculate the odds ratio.

Now, assume that 10% of the true ‘red meat consumers’ users were misclassified as non-consumers and 10% of the actual non-consumers were misclassified as red meat consumers among both the cases and controls.

b) What kind of misclassification is this?

c) Calculate the odds ratio and determine the direction of the bias, if any.

Solution