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session masteringbiology.com Sports & Rec I UFM length YouTube Google Home UMB Bank Kansas State Universi Home I Jimm... Sandwiches Apple Cloud Yahoo Bing Wikipedia Facebook Twitter LinkedIn ity My Lob and Mastering Mastering Biology: Assignments Chegg Study Guided Solutions and Chapter 12 The Endomembrane S Soved: Silicosis and Asbestosis Sl... BIOL 541 Cell Biology Close Chapte 12 Th Endomembrane System Chapter 12, Question 10 21 of 22 previous Part D Chapter 12, Question 10 What do you think happens to the silica particles or asbestos fibers when such cells die? Silicosis is a debilitating miner\'s disease that results from the ingestion of silica particles (such as sand or glass) by The fibers or particles released on cell death presumably are available for ingestion by macrophages, with the same end result. macrophages in the lungs. Asbestosis is a similarly serious disease caused by inhalation of asbestos fibers. The fibers or particles released on cel death presumably are available for ingestion by basophils, with the same end result. In both cases, the particles or fibers are found in lysosomes, and fibroblasts, which secrete collagen, are The fibers or particles released on cell death presumably are available for ingestion by eosinophils, with the same end result. stimulated to deposit nodules of collagen fibers in the lungs, leading to reduced lung capacity impaired The fibers or particles released on cell death presumably are available for ingestion by lymphocytes, with the same end result. breathing, and eventually death. Subm My Answers Give Up Part E How can cell death continue almost indefinitely, even after prevention of further exposure to silica dust or asbestos fibers? Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used. Reset Help release Because the fibers and and there is no damage mechanism to remove the m from the a cycle of uptake, lysosomal death, and fiber or particle s set particles up that can continue indefinitely, killing more and more cells. not digestible Ce lungs

Solution

Because the fibres and particles are not digestible and there is no mechanism to remove them from the cell, a cycle of uptake, lysosomal damage, cell death and fibre or particle release is set up that can contineu indifinitely, killing more and more cells.

These silica particles are taken by macrophages