Why do we have microbes to thank for the polymerase chain re

Why do we have microbes, to thank for the polymerase chain reaction? (How is the discovery of PCR related to the field of microbiology?) Explain clearly how one cycle of PCR works. What are some of the uses and advantages of PCR?

Solution

Microbes can survives in extreme condtion like the Thermus aquaticus is a species of bacteria that can tolerate high temperatures. It is the source of the heat-resistant enzyme Taq DNA polymerase, Most usefull enzyme in molecular biology used in the polymerase chain reaction (PCR) DNA amplification technique.

One PCR cycle includes include three succesive reaction

1. Denaturation

2. Primer annealing

3. DNA synthesis or Extension

PCR is a versatile method for amplifying defined target DNA sequences within the source of DNA it have wide range of application  including genotyping, cloning, mutation detection, sequencing, microarrays, forensics, and paternity testing