What is the expected proportion of progeny with recombinant
What is the expected proportion of progeny with recombinant genotypes at the C and E genes from a female who has the following karyotypes (the genetic distance between all adjacent loci is 10cM):
a) A-B-C-D-E/a-b-c-d-e
b) A-E-D-C-B/a-b-c-d-e
c) A-E-D-C-B/a-e-d-c-b
Solution
If the combination is said to occur between C & E, following are the possibility of progenies:
a.)
i) If recombination occurs between C and D Progeny will be: ABCde/abcDE
ii) If it occures between d and e : Result will be ABCDe/abcdE
b.)
i) Recombination between E and D result will be: AEdcb/aBCDe
ii) Recombination of c and d will form AEDcb/aBCde
c.)
i) Recombination between E and D will result will be: AEdcb/aeDCB
ii) Recombination between c and d will form AEDcb/aedCB
