You are working with a 125 million bp human chromosome 1 cen

You are working with a 125 million bp human chromosome (1 centimorgan = 1 million bp), and wish to use markers to map new genes via linkage. In theory, what are the minimum number of markers/loci you need to map genes to this chromosome?

Solution

1 centimorgan=1 million bp

=> 125million bp=125 centimorgan

To create a linkage we need 2 points.Therefore number of loci=number of chromosome/2

=>125/2=62.5=62

The minimum number of loci are 62 .