The photic sneeze reflex also known as the Autosomal Dominan

The photic sneeze reflex, also known as the Autosomal Dominant Compelling Helio-Ophthalmic Outburst syndrome (ACHOO syndrome), causes individuals to sneeze in response to stimuli such as looking at the sun. In the overall population, approximately 35% of individuals are affected. Estimate the following. Show your work and carry to 4 decimal places.

What is the frequency of the recessive allele and what percentage of individuals are heterozygous?

In a group of 500 individuals, how many individuals are homozygous dominant for the ACHOO genotype?

The photic sneeze reflex, also known as the Autosomal Dominant Compelling He Ophthalmic Outburst syndrome (ACHOO syndrome), causes individuals to sneeze in response to stimuli such as looking at the sun In the overall population, approximately 35% of individuals are affected. Estimate the following. your work and carry to 4 decimal places. 9. What is the frequency of the recessive allele? (2 pts.) 10. What percentage of individuals are heterozygous (2 pts.) 11. a group of 500 individuals, how many individuals are homozygous dominant for the A In genotype (2 pts.)

Solution

The frequency of the \"a\" allele.

The frequency of aa is 35%, which means that q² = 0.35, by definition. If q² = 0.35, then q = 0. 5916, again by definition. Since q equals the frequency of the a allele, then the frequency is 59.16%.

The frequency of the \"A\" allele.

Since q = 0.35, and p + q = 1, then p = 0.4048; the frequency of A is by definition equal to p, so the answer is 40.48%.

The frequency of AA is equal to p², and the frequency of Aa is equal to 2pq. So, using the information above, the frequency of AA is 16.53% (i.e. p² is 0.4048 x 0.4048 = 0.1653) and Aa is 47.89% (2pq = 2 x 0.4048 x 0.5916 = 0.4789).