FreeEnergy Changes of Glycol tic Reactions in Erythrocytes E

Free-Energy Changes of Glycol tic Reactions in Erythrocytes. Examine the data above and succinctly answer the following questions: What do reactions 1, 3, and 10 have in common? What is the significance of this commonality on the overall biochemical pathway these reactions are involved in? If the concentrations of glucose and ATP in reaction 1 were both 1 what must the minimal concentrations of glucose 6-phosphate and ADP be to drive the reaction in the reverse direction at 25 degree Celsius?

Solution

A) all 3 reactions are spontaneous reaction, having negative delta G value.

C) For the reaction to take place in the reverse direction, G must be positive and large.

G = G°\' + RT ln ([products]/[reactants]).

      For G to become positive, the concentration of products ( glucose 6 phosphate and ADP ) must be greater than the reactants ( Glucose and ATP). therefore, the minimal concentration of glucose 6 phosphate and ADP must be greater than 1uM.